Are you a patient with type 2 diabetes ?

 

Your family has a history of diabetes ? Are you concerned or suffering from complications of diabetes ? We are here for you with a personalized healthcare approach.

 

Being diagnosed with diabetes (T2D), living with it and being concerned with the potential serious complications is a heavy burden. The experienced professionals of OPTITHERA are here to help you by providing genomic insights to assist your doctor guide your personalized healthcare with prevention in mind. Below are some frequently asked questions, If you’d like to get more information, please contact us.

 
FAQS

DIABETES

Diabetes is a chronic disease that occurs when the pancreas is no longer able to make insulin, or when the body cannot make good use of the insulin it produces. Not being able to produce insulin or use it effectively leads to raised glucose levels in the blood (known as hyperglycaemia).

Over the long-term high glucose levels are associated with damage to the body and failure of various organs and tissues. For more information :  https://www.idf.org/aboutdiabetes/what-is-diabetes.html.

“There are currently 425 million adults with diabetes worldwide and this number is expected to increase to 640 million by 2040. 1 in 11 adults has diabetes worldwide”. – IDF Atlas https://www.diabetesatlas.org

With its increasing risk of related morbidity, including macrovascular (coronary artery disease (CAD), myocardial infarction or stroke) and microvascular (diabetic nephropathy, diabetic retinopathy, peripheral neuropathy) complications, diabetes is one of the most challenging health problems of the 21st century touching every country of the globe and all types of people.

The underlying concept of PRECISION MEDICINE is that health care is individually tailored on the basis of a person’s genes, lifestyle and environment.

POLYGENIC RISK SCORES

A Polygenic Risk Score (PRS) is a number that defines the level of risk a person has to develop a disease or its complications based on the genomic profile of that person.

 

OPTITHERA combined ‘’big genomic data’’ (6 million genomic variants per individual) with a comprehensive set of clinical and outcome data from thousands of patients with diabetes, collected prospectively over 10 years.

 

THE DATABASE

 

The Polygenic Risk Score (PRS) and algorithms developed by OPTITHERA can stratify patients with diabetes into different groups based on their predicted risk of renal and cardiovascular complications and response to therapy. These PRS optimize cost-utility by effectively timing treatment and eliminating insufficient or excessive treatment regimens.

POLYGENIC RISK SCORES

A Polygenic Risk Score (PRS) is a number that defines the level of risk a person has to develop a disease or its complications based on the genomic profile of that person.

 

OPTITHERA combined ‘’big genomic data’’ (6 million genomic variants per individual) with a comprehensive set of clinical and outcome data from thousands of patients with diabetes, collected prospectively over 10 years.

 

THE DATABASE

 

The Polygenic Risk Score (PRS) and algorithms developed by OPTITHERA can stratify patients with diabetes into different groups based on their predicted risk of renal and cardiovascular complications and response to therapy. These PRS optimize cost-utility by effectively timing treatment and eliminating insufficient or excessive treatment regimens.

DATA CONFIDENTIALITY

 

Data confidentiality is at the core of OPTITHERA’s priorities. Co-founder’s
Pavel Hamet & Johanne Tremblay are experts in the domain of ethics and confidentiality having written multiple publications on the subjects:

The Gatekeeping Function in Personalized Medicine Initiatives
Artificial intelligence in medicine

FAQS